Yes. There are several options, however, chose them wisely.
1A) Tag synonyms (here's a current list). If you want to prevent sync from coming back, and it rather refers to synchronization, just suggest or create a tag synonym for it. All future questions tagged with sync will automatically converted to synchronization.
1B) Merge tags. This is basicly merging synonyms. It's the same as 1A with an additional step of retagging (merging) all previously mistagged (e.g., sync) with the new tag (e.g., synchronization).
31) Burninate and blacklist tags. This is a very drastic step and should only apply to obvious generic or meta tags, like monero (this one should be blacklisted by default). Prior to blacklisting a tag, there needs to be a discussion on the meta here for each single request and it will only happen if there is a broad consensus and the reasons are obvious.
As you can see 1A and 1B are almost the same. And between them and '31' there is a huge gap. For tags like mining or transaction I would suggest (if there is really consensus that they are too generic) to constantly remove or retag them rather than blacklisting them. Unused tags will be removed from the system every day.
And while we are at it: Don't be scared about mining or transaction at this point. In my eyes they are valid. On Ethereum stack exchange there are only 266 transaction questions (9.7%) and 194 mining (7.1%) questions. At this stage it might be also worth to read up through this meta thread from short after the Ethereum public beta launched, and also this thread with a good comment by Robert Cartaino:
Tags aren't like questions that have too many answers. They are supposed to organize somewhat large swaths of subject matter so folks can find and follow their general interests. Some of those interests are more specific while others remain somewhat general.